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Test Results (Skin)

Results of a Study Evaluating the
Use of a Dietary Supplement Formula in the
Management of Age-Related Skin Changes in
Women with Moderate to Severe Wrinkling
of the Periorbital Area

Irwin Kantor, MD, FAAD,*1 Louise A. Donikyan, DO,1
Randi Simon, BS,1 Bernd Wollschlaeger, MD2
1RTL, Inc., Hackensack, New Jersey
Clinical Assistant Professor of Medicine and Family Medicine,
University of Miami School of Medicine, Miami, Florida

Context:   The relationship between dietary supplementation and the repair of aging skin is unclear.

Objective:   To assess the safety and efficacy of a dietary formulation for the improvement of age-related degenerative skin changes in women.

Methods:  Using a blinded, randomized, parallel design, a total of 40 women, ages 35-65 years were enrolled and divided into approximately balanced groups with 38 women completing this eight-week, four-visit study. Recommended daily doses of the study product, a dietary collagen formulation (Toki), were 7.5 g 
(given to Group A) and 8.5 g 
(given to Group B). Both investigator and subjects assessed skin wrinkling and other skin characteristics in the periorbital area as well as overall facial aging.

Main Outcome Measures:   Safety and efficacy of a dietary collagen formulation when used to improve periorbital wrinkling, aging, sagging and puffiness and periorbital overall facial aging.

Results:     The consumption of the dietary collagen formulation resulted in a highly statistically significant improvement in periorbital wrinkling, in periorbital aging and in periorbital overall facial aging. The investigator’s mean global improvement scores of overall facial aging as compared to baseline photographs were highly significant.

Conclusion:

In women with age-related skin changes, a dietary collagen formulation (Toki) significantly improved periorbital wrinkling, periorbital aging, and periorbital overall facial aging with minimal adverse effects.

Biotech Approved. FDA Compliant. Classed as a Natural Food Supplement. The only side-effects reported are great ones! As well as drastic relief, early users have all reported improvements in fine lines, wrinkles, firmer breasts, cellulite, scars and stretch-marks! Also it’s noticed to improve hair, nails and energy levels.